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News articleYahoo Finance· January 21, 2026

Johnson & Johnson reports Q4 and Full-Year 2025 results

View original at finance.yahoo.com
Johnson & Johnson reports Q4 and Full-Year 2025 results 2025 Fourth-Quarter reported sales growth of 9.1% to $24.6 Billion with operational growth of 7.1%* and adjusted operational growth of 6.1%*; 2025 Fourth-Quarter earnings per share (EPS) of $2.10 and adjusted EPS of $2.46, both include $(0.10) due to the acquisiti…
Opening lines of the source · Yahoo Finance · short snapshot — read the full document at the original

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  • 2026 adjusted operational EPS guidance of $11.28-$11.48 with midpoint of $11.38 representing 5.5% growth

    80% confidence
  • 2026 adjusted EPS guidance of $11.43-$11.63 with midpoint of $11.53 representing 6.9% growth

    80% confidence
  • TREMFYA is the only IL-23 inhibitor proven to inhibit structural joint damage in active psoriatic arthritis

    80% confidence
  • INLEXZO achieved 74% disease-free survival at one year in BCG-unresponsive high-risk papillary-only NMIBC

    80% confidence
  • DARZALEX FASPRO is the first/only FDA-approved treatment for high-risk smoldering multiple myeloma

    80% confidence
  • 2026 adjusted operational sales growth guidance of 5.4%-6.4% with midpoint of 5.9%

    80% confidence
  • RYBREVANT FASPRO + LAZCLUZE has the shortest administration time for first-line combination regimen

    80% confidence
  • 2026 operational sales guidance of $99.5B-$100.5B with midpoint of $100.0B representing 6.2% growth

    80% confidence
  • TECVAYLI + DARZALEX FASPRO demonstrated superior PFS and OS vs. standard of care in second-line multiple myeloma

    80% confidence
  • Nipocalimab is the first/only investigational FcRn blocker showing potential to reduce SLE activity in Phase 2

    80% confidence
  • AKEEGA demonstrates 54% reduction in disease progression in BRCA2-mutated metastatic castration-sensitive prostate cancer

    80% confidence
  • 2026 reported sales guidance of $100.0B-$101.0B with midpoint of $100.5B representing 6.7% growth

    80% confidence
  • Subcutaneous amivantamab achieved 45% overall response rate with 7.2-month median duration in recurrent/metastatic head and neck cancer

    80% confidence

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Q4 2026 Clinical Catalyst Season: Big-Pharma Data Flow, Regulatory Milestones, and a Thin AI-Drug Fringe
October 2026 conferences (EASD, IGCS, NACFC, HFSA) are producing a dense run of late-stage readouts from Novo Nordisk, Lilly, Roche, Bayer, Vertex and Galderma. Regulatory milestones are scheduled behind them: the ivonescimab BLA PDUFA date on 2026-11-14, FDA acceptance of Roche's vamikibart BLA, and Scholar Rock's EMA resubmission. The AI-and-finance angle is peripheral. It consists of the AI-designed drug Rentosertib and QAIAx, a speculative microcap whose trial claims (the QIII pilot, anticipated 2027-01-01, and a patent update) are forecasts and filings rather than data, so they warrant skepticism.
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
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ING Group
Both facts record the same metric (shares_outstanding) for ING Group at the identical observation date (2025-12-31). FACT A states 2,902,437,688 shares; FACT B states 2,902 million shares (2,902,000,000). The difference is 437,688 shares (~0.015%). This is a genuine value conflict, though the discrepancy appears to result from FACT B rounding to the nearest million while FACT A provides the precise count.
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